Introduced in 1999, Parietex™ Composite (PCO) mesh was the first to offer a resorbable collagen barrier on one side to limit visceral attachments and a three-dimensional polyester knit structure on the other to promote tissue ingrowth and ease of use. This balance of material properties produces superior cellular proliferation when compared to polypropylene mesh in vitro1 and works with the body’s natural systems to provide rapid fibrous ingrowth,2 minimal shrinkage3,4 and strong tissue integration5. With more than 10 years of documented clinical effectiveness, Parietex™ PCO mesh was ahead of its time and remains the procedural standard that others strive to reach.
All of Covidien's Parietex™ products are created from a macroporous polyester material whose properties invite healthy tissue integration and mesh compliance while reducing encapsulation.1
Features and Benefits
| Feature | Benefit |
|---|---|
| Composite mesh with resorbable collagen film | Proven effective, with more than 10 years of documented success |
| Composite mesh with resorbable collagen film | Proven safe based on a mean clinical follow-up of four years in a prospective, multicenter human trial7 |
| Composite mesh with resorbable collagen film | Lower incidences of visceral attachments in comparative and animal studies5,6 |
| Hydrophilic, macroporous polyester material | Stronger incorporation into the abdominal wall in prospective and comparative animal studies3,6 |
| Hydrophilic, macroporous polyester material | Incites excellent fibrous ingrowth and a neoperitoneum versus the inflammatory encapsulation of other meshes2 |
| Hydrophilic, macroporous polyester material | Produces superior cellular proliferation when compared to polypropylene mesh in vitro1 |
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Lefranc, et al. (2009). PET vs. PP mesh constructs and their influence on L929 fibroblasts adhesion and proliferation. HS/AHS. Springer. Berlin, Hernia. 13: 64-72.
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Duffy, A., et al. (2004). “Comparison of Two Composite Meshes Using Two Fixation Devices in Porcine Laparoscopic Ventral Hernia Model.” Hernia: The World Journal of Hernia and Abdominal Wall Surgery, 8, 358-364. Microscopy showed a new mesothelial layer on the visceral surface of PCO Mesh but mainly inflammatory tissue with only a little mesothelium covering the visceral surface of Composix.
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Burger, J.W., et al. (2006). “Evaluation of New Prosthetic Meshes for Ventral Hernia Repair.” Surgical Endoscopy. Parietex™ Composite Mesh (11.2%), Sepramesh (10.4%), and Tutomesh (4.4%) resulted in decreased surface coverage with adhesions (p. 1323, Table 3). Parietex™ Composite Mesh (49.8%), Prolene (34.7%), Ultrapro (34.7%), and Sepramesh (43.3%) resulted in the most mesh incorporation (p.1323, Table 4).
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Rosen, M.J. (2009). “Polyester-based Mesh for Ventral Hernia Repair: Is It Safe?” American Journal of Surgery, 197, 353-359.
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Jacob, B., et al. (2007). “Tissue Ingrowth and Bowel Adhesion Formation in an Animal Comparative Study, Polypropylene Versus Proceed Versus Parietex™ Composite Mesh.” Surgical Endoscopy, 21, 629-633. PCO Mesh prevented most adhesions and incited excellent fibrous ingrowth. It also allowed a neoperitoneum to form on the visceral surface of the mesh (p. 632, C2, L36-39). Mean area of adhesions was significantly less for PCO than for either Proceed or PP (Table 1, p. 630). The anti-adhesive collagen visceral layer of PCO Mesh is more effective in preventing adhesions than is the polydioxanone polymer of Proceed mesh (p. 632, C2, L17-19).
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Gonzalez, R., et al. (2004). “Resistance to Adhesion Formation: A Comparative Study of Treated and Untreated Mesh Products Placed in the Abdominal Cavity.” Hernia: The World Journal of Hernia and Abdominal Wall Surgery. The ideal results of a smooth incorporation of the hernia mesh into the abdominal wall were seen only with Parietex™ Composite Mesh (p. 218, C2, L53-56).
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Balique, G. (2005). “Intraperitoneal Treatment of Incisional and Umbilical Hernias Using an Innovative Composite Mesh: Four-year Results of a Prospective Multicenter Clinical Trial.” Hernia: The World Journal of Hernia and Abdominal Wall Surgery, 9, 68-74.
Frequently Asked Questions
| Question | Answer |
|---|---|
| What Material is this made of? | Polyester, with a three Dimensional Weave Material |
| Can I cut the PCO Mesh? | Not recommended |
| What is the collagen made of? | Porcine collagen, Polyethlene Glycol, Glycerol |
| Do I need to soak the PCO in saline prior to insertion? | Yes |
| Is there clinical data to support claims? | Yes |
Not available in all markets.
Covidien products should only be used by responsible and experienced surgical practitioners.
